Glaucoma Treatment by Cyclo-coagulation Using High Intensity Focused Ultrasound (HIFU)

Inclusion Criteria: * Refractory Glaucoma * IOP \> 21 mm Hg * No previous intraocular surgery or laser treatment during the 90 days before HIFU day * Age \> 18 years * Informed consent sgned by the subject Exclusion Criteria: * Normal Tension Glaucoma * Glaucoma drainage device implanted and still present in the eye to be treated * History of ocular or retrobulbar tumor * Ocular infection within 14 days prior to the HIFU procedure * Aphakic patient * Ocular disease other than glaucoma that may affect assessment of visual and/or IOP (choroidal hemorrhage or detachment, lens subluxation, thyroid ophthalmopathy, proliferative diabetic retinopathy, clinical significant macular edema) * Pregnant or breast-feeding women, or lack of contraception use among women likely to have a child