Prediction of Chronic Pain by the Pain Monitor

Hopital Foch6 enrolled

Overview

The skin conductance algesimeter (Pain Monitor™, Med-Storm Innovation AS, NO-0264 Oslo, Norway)) reflects the sympathetic nervous system by the measurement of the skin conductance of the palm of the hand. SCA detects nociceptive pain fast and continuously, specific to the individual, with higher sensitivity and specificity than other available objective methods. The skin conductance response to a calibrated noxious stimulus varies among patients. It defines two types of people depending on its magnitude. The investigators assume that the importance of skin conductance response to a noxious stimulus predicts the occurrence of chronic pain in patients operated by thoracotomy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Surgery

Interventions

Pain MonitorDEVICE

Measurement of cutaneous conductance

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * adult patients of both sexes * planned pulmonary resection for cancer performed by a posterolateral thoracotomy * thoracic epidural analgesia Exclusion Criteria: * pregnancy, * morbid obesity, * insulin-dependent diabetes with dysautonomia, * inability to proceed with anesthesia using the BIS signal, * known allergy to remifentanil, propofol, atracurium or to levobupivacaine, * contra-indication to nefopam * contra-indication to ketoprofen

Locations (2)

CHU Strasbourg

Strasbourg, France

Hopital Foch

Suresnes, Île-de-France Region, France

Outcomes

Primary Outcomes

Prediction of chronic pain

Prediction of chronic pain by the measurement of skin conductance

Time frame: one year after surgery

Secondary Outcomes

Prediction of the postoperative pain

Prediction of the postoperative pain by the measurement of skin conductance. Postoperative pain is assessed (pain score) at least twice each day at rest and during mobilisation.

Time frame: 5 days postoperatively

Prediction of the postoperative antalgic requirement

Prediction of the postoperative analgesic requirement by the measurement of skin conductance. The analgesic requirement is evaluated by the amount of epidural analgesics.

Time frame: 5 days postoperatively

Prediction of the postoperative antalgic requirement by the genetic study

Time frame: One year after surgery

Effect of remifentanil on skin conductance

Skin conductance is measured before and after a calibrated noxious stimulus. This test is performed after the induction of anesthesia (propofol) and a first time before remifentanil administration and a second time after.

Time frame: One hour after anesthesia

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.