Successful Pregnancy and Delivery After AOA

Maria Fertility Hospital100 enrolled

Overview

Artificial oocyte activation with strontium chloride or calcium ionophore improves fertilization, embryo quality, pregnancy and delivery rate in women who showed complete fertilization failure or low fertilization rates

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Enrollment

100

Conditions

Infertility

Interventions

Calcium ionophoreOTHER

Oocytes were activated with calcium ionophore after ICSI

Strontium chloride (SrCl2)OTHER

Oocytes were activated with strontium chloride after ICSI

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Fertilization rate was less than 30% after conventional ICSI. * Fertilization rate was less than 50% after ICSI with calcium ionophore. * Repeated complete fertilization failure or low fertilization rates following ICSI in previous cycles Exclusion Criteria: * Fertilization rate was more than 30% after conventional ICSI * Fertilization rate was more than 50% after ICSI with calcium ionophore. * Successful pregnancy and delivery after ICSI in previous cycles

Locations (1)

Maria Fertility Hospital

Seoul, South Korea

Outcomes

Primary Outcomes

Fertilization rate

Time frame: 18 hours

Secondary Outcomes

Embryo quality

Time frame: 3 Days

Pregnancy and Implantation rates

Time frame: 2 months

Assessment of Infant health care

This assessment is according to the standard set by the National Health Insurance Service (NHIS) in Korea.

Time frame: birth and at 3, 6, 12, 24, 36, 60, and 72 months

Data from ClinicalTrials.gov

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