Circadian Rhythm of Melatonin in Burns

Shriners Hospitals for Children86 enrolled

Overview

Evaluate markers and postulated effectors of the endogenous circadian pacemaker in children admitted to the burn intensive care unit.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sleep Burns

Eligibility

Sex: ALLMin age: 5 YearsMax age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 5-18 years old Exclusion Criteria: * anoxic brain injury * preexisting neurological disorder * pre-existing sleep disorder * no informed consent or HIPAA release

Locations (1)

Shriners Hospital for Children

Cincinnati, Ohio, United States

Outcomes

Primary Outcomes

sleep status

actigraphy, polysomnography

Time frame: 48hrs

Secondary Outcomes

urinary melatonin

Time frame: every 2 hours for 48 hrs

Data from ClinicalTrials.gov

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