ENhancing Maturation of Autogenous Arteriovenous Hemodialysis Access by Aggressive surveillaNCe With Duplex and Endovascular Treatment

Seoul National University Hospital150 enrolled

Overview

The aim of this study is to evaluate whether Aggressive duplex surveillance after vascular access surgery with native vein for hemodialysis can increase the maturation rate of arteriovenous fistula. This study will be conducted as a single center, prospective, 1:1 randomized study. Enrolled patients will be randomized as a control group (Physical exam at 2 and 4 weeks after surgery) and duplex group (duplex study and physical exam at 2 and 4 weeks after surgery). Maturation of arteriovenous fistula will be evaluated at 8 weeks after surgery by duplex in all patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

150

Conditions

End Stage Renal Disease

Interventions

Duplex ultrasonography

Eligibility

Sex: ALLMin age: 20 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * end stage renal disease * newly formed hemodialysis access with native vein * 20\~70 years Exclusion Criteria: * hemodialysis access surgery with ePTFE graft * hemodialysis access surgery with basilic vein transposition * hemodialysis access surgery with brachial vein transposition * cephalic vein \< 2.5mm in diameter * radial artery diameter \<2.0mm in radiocephalic arteriovenous fistula

Outcomes

Primary Outcomes

hemodialysis access maturation rate

Time frame: 8 weeks after surgery

Secondary Outcomes

factors predicting maturation failure