The purpose of this prospective study is to investigate the association between the amount of residual urine and asymptomatic bacterial prostate infection with the occurrence of recurrent (\>2 /year) symptomatic urinary tract infections in patients suffering from chronic (\> 1 year) spinal cord injury (SCI) and neurogenic lower urinary tract dysfunction performing intermittent catheterization. The following hypotheses will be tested: 1. The amount of residual urine after intermittent catheterization is significantly greater in SCI patients suffering from frequent (\>2 /year) urinary tract infections compared to those without. 2. The incidence of asymptomatic bacterial prostate infections is significantly higher in SCI patients suffering from frequent (\>2 /year) urinary tract infections compared to those without.
To investigate the association between the amount of residual urine and asymptomatic bacterial prostate infection with the occurrence of recurrent (\>2 /year) symptomatic urinary tract infections in patients suffering from chronic (\> 1 year) spinal cord injury (SCI) and neurogenic lower urinary tract dysfunction performing intermittent catheterization, patients perform self-catheterization twice (before and after urodynamic testing. After each catheterization, residual urine is assessed by ultrasound. Prior to urodynamic testing, prostate massage is performed, bacterial cultures of the fluid and the urine are initiated and the results of these cultures will be analysed .
Study Type
OBSERVATIONAL
Enrollment
60
residual urinary volume assessed by ultrasound after bladder catheterization urinary cultures taken before and after prostate massage
Swiss Paraplegic Centre
Nottwil, Canton of Lucerne, Switzerland
amount of residual urine
determined by ultrasound
Time frame: change from self-catheterization 10 minutes before and 10 minutes after urodynamic assessment
bacterial prostate infection
urinary culture
Time frame: 5-10 minutes before and after prostate massage
bacteriuria
urine dip stick
Time frame: 5-10 minutes before and after prostate massage
number of leucocytes in urine
urine dip stick
Time frame: 5-10 minutes before and after prostate massage
number of erythrocytes in urine
urine dip stick
Time frame: 5-10 minutes before and after prostate massage
patient characteristics
age
Time frame: day 0
type of neurogenic bladder dysfunction
Time frame: day 0
type of catheter used for intermittent catheterization
Time frame: day 0
annual rate of symptomatic urinary tract infections
Time frame: day 0
patient characteristics
sex
Time frame: day 0
patient characteristics
time since spinal cord injury
Time frame: day 0
patient characteristics
level and degree of spinal cord injury (ASIA impairment score)
Time frame: day 0
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