Compassionate Use of an Intravenous Fish Oil Emulsion in Infants With Cholestasis

Inclusion Criteria: Cholestasis defined as either * serum bilirubin \> 2mg/dL (two measurements at least 8d apart) that has not responded to 4 weeks of intralipid being reduced to 1 g/kg/d and trace minerals being limited to twice weekly, OR * serum bilirubin \> 6 mg/dL (single measurement) and rising, in the absence of proven or suspected sepsis Exclusion Criteria: * Age \> 1y at time that omegaven is started * Not expected to survive at least 30 days * Fish allergy in a first degree relative * Hemodynamic instability * Coagulopathy * Not likely to require PN for \> 30d * Not expected to survive \> 30d