This study was designed to analyze whether initiation of the NICHD Neonatal Research Network SUPPORT trial was followed by a change in frequency of endotracheal intubation the delivery room in non-participants and whether these changes were associated with changes in management and outcomes. The investigators hypothesized that the investigators would observe following the initiation of the SUPPORT trial a 33% reduction in the rate of intubation in the delivery room among non-participants preterm infants at Parkland Memorial Hospital.
Study Type
OBSERVATIONAL
Enrollment
3,843
University of Texas Southwestern
Dallas, Texas, United States
Endotracheal intubation in the delivery room
Frequency of endotracheal intubation in the delivery room
Time frame: In the delivery room (1 day)
Continuous positive airway pressure in the delivery room
Frequency of continuous positive airway pressure in the delivery room
Time frame: In the delivery room (1 day)
Endotracheal intubation in the first four hours after admission
Frequency of endotracheal intubation in the first fours after admission to the neonatal intensive care unit
Time frame: First four hours after admission
Endotracheal intubation until four hours after admission
Frequency of endotracheal intubation between birth and four hours after admission in the neonatal intensive care unit
Time frame: Between birth and 4 hours after admission
Admninistration of surfactant
Frequency of admninistration of surfactant any time between birth and 2 days of age
Time frame: Any time between birth and 2 days of age
Pneumothorax
Pneumothorax any time before discharge or transfer or 12 months of age (whichever comes first)
Time frame: Any time before discharge or transfer or 12 months of age (whichever comes first)
Bronchopulmonary dysplasia
Chronic changes on chest radiograph and oxygen requirement (fractional inspiratory concentration of oxygen greater than 0.21) for at least 28 days
Time frame: 28 days
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Necrotizing enterocolitis
Necrotizing enterocolitis (at least stage II, modified Bell's classification) any time before discharge or transfer or 12 months of age (whichever comes first)
Time frame: Any time before discharge or transfer or 12 months of age (whichever comes first)
Duration of mechanical ventilation
Duration of invasive mechanical ventilation until discharge or transfer or or 12 months of age (whichever comes first)
Time frame: Until discharge or transfer or 12 months of age (whichever comes first)
Maximum oxygen concentration
Maximum inspiratory oxygen concentration until discharge or transfer or 12 months of age (whichever comes first)
Time frame: Until discharge or transfer or 12 months of age (whichever comes first)
Severe retinopathy of prematurity
Severe retinopathy of prematurity (at least stage III, international classification) until discharge or transfer or 12 months of age (whichever comes first)
Time frame: Until discharge or transfer or 12 months of age (whichever comes first)
Mortality
Mortality until discharge or transfer or 12 months of age (whichever comes first)
Time frame: Until discharge or transfer or 12 months of age (whichever comes first)
Severe brain lesion on imaging
Cystic periventricular leukomalacia or grade III or IV intraventricular/ periventricular hemorrhage detected by ultrasonogram any time before discharge or transfer or 12 months of age (whichever comes first)
Time frame: Any time before discharge or transfer or 12 months of age (whichever comes first)