Trial of Effect of High-frequency Transcranial Magnetic Stimulation in the Management of Borderline Personality Disorder

Tehran University of Medical Sciences40 enrolled

Overview

This study is going to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on Borderline Personality Disorder patients symptoms.

There is a great body of literature about the positive effects of rTMS therapy on various psychiatric disorders. In this study we are going to evaluate the effects of high-frequency rTMS over the left dorsolateral prefrontal cortex (DLPFC)region in borderline personality disorder (BPD) patients. patients will be assessed by subjective measures for BPD.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Borderline Personality Disorder

Interventions

rTMSDEVICE

Patients undergone 10 session of high-frequency rTMS therapy over their left DLPFC

sham rTMSDEVICE

Patients will undergo ten session of sham rTMS.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinically diagnosed borderline personality disorder according to DSM IV. Exclusion Criteria: * Epilepsy * Any metal device * Psychotic disorders * Bipolar mood disorder type 1

Outcomes

Primary Outcomes

Patients' reports

changes in subjective measures from baseline to tenth day of treatment

Time frame: Change from baseline to two weeks

Secondary Outcomes

patient's report

change in subjective measures from baseline to 1 month after treatment

Time frame: Change from baseline to 1 month

Patient's report

change in subjective measures form baseline to 3 month after treatment

Time frame: Change from baseline to 3 month

Data from ClinicalTrials.gov

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