A Multicenter, Proof-Of-Concept Study Of Intravitreal AL-78898A In Patients With Geographic Atrophy (GA) Associated With Age-Related Macular Degeneration (AMD)

Inclusion Criteria: * Ability to provide informed consent and comply with the protocol. * Diagnosis of bilateral geographic atrophy (GA) of the macula secondary to age-related macular degeneration, confirmed within 14 days prior to randomization. * Study eye: Maximum best-corrected visual acuity (BCVA) of 55 letters (20/80 Snellen equivalent) and a minimum BCVA of 20 letters (20/400 Snellen equivalent) at screening * BCVA of 20 letters (20/400 Snellen equivalent) or better in the non treated eye at screening without conditions other than AMD that, in the opinion of the investigator, could cause a rapid loss of vision. * Other protocol-defined inclusion criteria may apply. Exclusion Criteria: * Any history or current evidence of exudative ("wet") AMD in study eye. * Retinal disease other than AMD in the study eye. * Any ophthalmologic condition in study eye that reduces the clarity of the media and that, in the opinion of the Investigator interferes with ophthalmologic examination, such as advanced cataract or corneal abnormalities. * Any ophthalmologic condition in study eye that prevents adequate imaging of the retina judged by the site or reading center. * A history or current medical diagnosis of glaucoma or ocular hypertension in study eye. * Any ophthalmic condition in study eye that may require surgery during the study period. * Current ocular or periocular infection in the study eye. * History of any disease or current use of medication expected to cause systemic or ocular immunosuppression, such as RESTASIS®. * History of uveitis or endophthalmitis in the study eye. * History of intraocular surgery (including cataract surgery) in the study eye within 90 days prior to dosing. * History of intravitreal or periocular injection in the study eye at anytime. * Participation in another interventional clinical study, or use of any experimental treatment for AMD or any other investigational new drug within 6 weeks or during active period of drug (whichever is longer) prior to the start of study treatment. * History of any medical or psychiatric condition, or substance abuse, that in the Investigator's opinion is likely to interfere with the patient's participation in the study, or likely to cause serious adverse events during the study. * Women of child bearing potential UNLESS they are using a highly effective method of birth control. * Known or suspected allergy or hypersensitivity to fluorescein or other injectables. * Other protocol-defined exclusion criteria may apply.