The aim of the ETPOS study is to describe differences in transfusion habits throughout Europe and to correlate these habits to perioperative outcome parameters. Special focus is put on the number of PRBCs (packed red blood cells) transfused and the ratio of PRBCs to other blood products or coagulation factors in the operating room. Furthermore the motivation of physicians to transfuse PRBC and blood products in the operating room will be investigated.
In European patients undergoing elective non-cardiac surgery receiving at least one PRBC(packed red blood cells) during their surgery it is proposed to: 1. Evaluate evidence of differences in the standard of peri-operative transfusion care in different healthcare systems within Europe, and the use of blood conserving techniques. 1. Evaluate the ratio of transfusion of PRBC to blood products in the operating room 2. Evaluate which factors determine transfusion of PRBC (is it patient's haemodynamics / haemoglobin threshold/ pressure from the surgeon / acute brisk bleeding / else) and blood products (ratio to PRBC / POC (point of care) monitoring/ per protocol/ else) in the operating room 2. Evaluate whether there are factors in transfusion therapy that are associated with outcome (in-hospital mortality and unplanned admission to ICU(Intensive Care Unit).)
Study Type
OBSERVATIONAL
Enrollment
6,066
University hospital "Merkur"
Zagreb, Croatia
Faculty Hospital Brno
Brno, Czechia
North Estonian Center
Tallinn, Estonia
University Hospital Tübingen University, Germany
Tübingen, Germany
Aretaieion University Hospital
Athens, Greece
Tel Aviv Medical Center
Tel Aviv, Israel
Hospital Vall d Hebron
Barcelona, Spain
Hospital Clínico Universitario de Valencia
Valencia, Spain
Sahlgrenska University Hospital
Gothenburg, Sweden
Amount of PRBC and blood products and coagulation factors transfused
Amount of packed red blood cells and blood products and coagulation factors: fresh frozen plasmas (FFPs), platelets (PTs) and tranexamic acid transfused
Time frame: The Time point at which outcome measure is assessed is during surgery at Day 0
Factors determining transfusion of PRBC and blood products in different regions of Europe
Reasons for transfusion of PRBC(packed red blood cells)and blood products in different regions of Europe
Time frame: The Time point at which outcome measure is assessed is during surgery at Day 0
30-day mortality
Assesses on Day 30 whether patient is still alive or has died between day zero (Surgery) day 30 after surgery
Time frame: The Time point at which outcome measure is assessed is at Day 30 after Surgery
Unplanned admission to the ICU
Assesses on day 30 whether the patient had a Unplanned admission to the Intensive care unit(ICU) following surgery (day 0) until the day 30
Time frame: The Time point at which outcome measure is assessed is at Day 30 after Surgery
Type and frequency of usage of blood conserving techniques
Time frame: The Time point at which outcome measure is assessed is at Day 0, on Surgery Day
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