The purpose of this study is to determine if adding daily application of CPP-ACP containing paste for one year is superior to regular fluoride tooth brushing in preventing dental caries in high caries risk Thai preschool children.
The 6th National Oral Health Survey in Thailand 2006-2007 reported that 3-year-old children who resided in central part have the highest dental caries prevalence of 69.8 percent with dmft affecting 3.63 teeth on average. Fluoride is widely accepted as the most effective tool to caries prevention for initial caries lesions. Current best practice recommends twice-daily tooth brushing with fluoride toothpaste for dentate children. CPP-ACP can bolster the effects of fluoridated toothpaste alone to prevent caries.Currently, almost all clinical trials have investigated the effectiveness of CPP-ACP containing products in dental caries prevention and enhancing remineralization of initial carious lesion in the permanent dentition of young adolescents. There are no clinical studies of the effect of a CPP-ACP containing product to prevent dental caries in the primary dentition of young children.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
296
Apply once a day at school by school teacher, following fluoride toothbrushing after lunch
Apply once a day at school by school teacher, following fluoride toothbrushing after lunch.
Faculty of Dentistry, Thammasat University
Klongluang, Patumthani, Thailand
the Mean Number of Enamel Carious Lesion
tooth surface that was classified as ICDAS code 1-3
Time frame: one calender year
Quantitative Light-induced Fluorescence (QLF) Parameters
percent fluorescence loss, lesion area, lesion volume
Time frame: one calender year
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