Platelet Inhibition and Bleeding in Patients Undergoing Non-Cardiac Surgery

Medical University of Graz207 enrolled

Overview

The aim of the study is to evaluate if there is an association between platelet inhibition and surgery-related bleeding in patients undergoing non-cardiac surgery during dual antiplatelet therapy.

Study Type

OBSERVATIONAL

Enrollment

207

Conditions

Postoperative Bleeding

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * intake of Clopidogrel, Prasugrel, or Ticagrelor within the last 7 days * spontaneous bleeding or impeding surgery (major vascular surgery, intraperitoneal or intrathoracic surgery, ENT-surgery, orthopedic or trauma surgery, prostatic surgery) Exclusion Criteria: * concomitant medication with warfarin * renal insufficiency needing dialysis * concomitant therapy with GPIIB/IIIA Antagonists * expected duration of operation \>30min

Locations (1)

Department of Anesthesiology and Intensive Care Medicine, Medical University Graz

Graz, Austria

Outcomes

Primary Outcomes

increased risk of bleeding (according to TIMI definition)

Time frame: 24hours postoperatively

Data from ClinicalTrials.gov

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