Prospective Randomized Study of Glucocorticoids in the Impact of the Liver Function and the Prognosis After Hepatectomy of HCC

Eastern Hepatobiliary Surgery Hospital60 enrolled

Overview

The major drawback of hepatic pedicle clamping is ischaemia-reperfusion injury with impairment of liver function. Perioperative steroid administration has been advocated to reduce liver damage. The aim of this prospective, randomized study was to determine whether steroid administration can reduce liver injury and impact the prognosis

Study Type

OBSERVATIONAL

Enrollment

Conditions

Some Studies Shows That the Steroid Can Reduce the Injury of the I/R of the Liver

Interventions

Hydrocortisone sodium succinateDRUG

100mg/day

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 18-70 years old * diametre of the mass\>3cm. * hcc

Outcomes

Primary Outcomes

liver function

Time frame: six months

Data from ClinicalTrials.gov

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