Periodontal Therapy in Coronary Artery Patients

Federal University of Rio Grande do Sul93 enrolled

Overview

Gingival inflammation has been associated with cardiovascular diseases, including heart attack and stroke, because of elevation of blood risk markers such as cholesterol, glucose and C reactive protein. The treatment of gingival diseases decreases the concentration of these risk factors in the blood of cardiovascular patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Cardiovascular Diseases Atheroma Coronary Artery Disease

Interventions

Subgingival scaling and root planingDEVICE

Oral hygiene instruction and motivation will be provided altogether with scaling and root planing of all teeth affected by periodontitis under local anesthesia

Oral prophylaxisDEVICE

One session of supraginigval calculus removal

Eligibility

Sex: ALLMin age: 35 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 35 years and older * coronary artery disease * more than 10 teeth * chronic periodontitis defined as 2 non-adjacent teeth with probing depth 5+mm and periodontal attachment loss 4+mm Exclusion Criteria: * use of antibiotics in the last 6 months * periodontal therapy in the last 12 months

Locations (1)

Federal University of Rio Grande do Sul, School of Dentistry and University Hospital

Porto Alegre, Rio Grande do Sul, Brazil

Outcomes

Primary Outcomes

Changes in C reactive protein

Time frame: Baseline, 3, 6 and 12 months

Changes in flow-mediated dilation

Time frame: Baseline, 1, 3 and 6 months