Contribution of Pancreatic αcells Function to Blood Glucose Regulation in Chinese Type 2 Diabetics- the Effect of Sitagliptin on Glucagon Secretion, Insulin Secretion and Insulin Resistance in Chinese Type 2 Diabetics

Change From Baseline in Fasting Plasma Glucose (FPG)

Time frame: Baseline to 12 weeks

Change From Baseline in Postprandial Plasma Glucose (PPG)

Time frame: Baseline to 12 weeks

Change From Baseline in Insulin Sensitivity

The insulin sensitivity was detected by evaluating the glucose infusion rate (GIR) with euglycemic hyperinsulinemic clamp test.

Time frame: Baseline to 12 weeks

Change From Baseline in Insulin Sensitivity in Patients With Different BMI

The insulin sensitivity was detected by evaluating the glucose infusion rate (GIR) with euglycemic hyperinsulinemic clamp test.

Time frame: Baseline to 12 weeks

Change From Baseline in Pancreatic β Cell Function

The early phase insulin response (△I30/△G30) was adopted to determine β cell function.

Time frame: Baseline to 12 weeks

Change From Baseline in Pancreatic β Cell Function in Patients With Different BMI

The early phase insulin response (△I30/△G30) was adopted to determine β cell function.

Time frame: Baseline to 12 weeks

Change From Baseline in Pancreatic α Cell Function

The glucagon-AUC was adopted to show pancreatic α cell function.

Time frame: Baseline to 12 weeks

Change From Baseline in Pancreatic α Cell Function in Patients With Different BMI

The glucagon-AUC was adopted to show pancreatic α cell function.

Time frame: Baseline to 12 weeks