The aim of this study is to evaluate the effect of minimizing right ventricular pacing in dual-chamber pacemaker patients with sinus node disease (SND) and first degree atrioventricular block (AVIB)on exercise capacity, quality of life and other heart failure measures.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Prolonging atrioventricular (AV) delay to maximum 350 ms.
Standard atrioventricular (AV) delay - approximately 180/140 ms depending on heart rate.
Military Institute of Medicine
Warsaw, Poland
RECRUITINGOxygen uptake (cardiopulmonary exercise testing).
Time frame: 3 months
Left ventricular ejection fraction.
Assessed in echocardiography.
Time frame: 3 months
Quality of life
SF36 questionnaire.
Time frame: 3 months
Arrhythmia
24 hours Holter monitoring, pacemaker storage data.
Time frame: 3 months
Ventilatory anaerobic threshold (cardiopulmonary exercise testing)
Time frame: 3 months
VE/VCO2 slope (cardiopulmonary exercise testing).
Time frame: 3 months
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