A Proof of Principle Study of Aminolevulinic Acid (ALA) - Induced Fluorescence Detection in Resectable Non-Small Cell Lung Cancer

Inclusion Criteria: * Inclusion Criteria Patients (12 total patients with lung cancer) meeting eligibility criteria will be enrolled. * Preoperative diagnosis of either presumed or documented non-small cell lung cancer. * Tumor judged to be suitable for surgical resection based on preoperative evaluation of radiographic studies, pulmonary function tests, performance status and clinical judgment of surgeons at DHMC (Erkmen, Nugent) * Age ≥ 18 years old. * Population representative of our usual referral pattern including minority populations, women and those who are financially disadvantaged. * Subjects capable of giving informed consent Exclusion Criteria: * Pregnant Women * Women who are breast feeding * History of cutaneous photosensitivity * Porphyria, hypersensitivity to porphyrins, photodermatosis * Exfoliative dermatitis * History of liver disease within the last 12 months * Inability to comply with photosensitivity precautions associated with the study * Inability to give informed consent * AST, ALT, ALP or bilirubin levels greater than 2.5 times the normal limit at any time during the past 2 months * Plasma creatinine in excess of 180 umol/L * Women who are breast feeding * History of cutaneous photosensitivity * Porphyria, hypersensitivity to porphyrins, photodermatosis * Exfoliative dermatitis * History of liver disease within the last 12 months * Inability to comply with photosensitivity precautions associated with the study