Comparison of Sublingual Misoprostol and Intravenous Oxytocin in Active Management of the Third Stage of Labor

Rasha Mohammed Mohammed Badawi180 enrolled

Overview

Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor

Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor as The data from a pharmacokinetics study suggested that the bioavaiblitiy of misoprostol after sub-lingual administration was higher than those after oral or vaginal administration

Study Type

OBSERVATIONAL

Enrollment

180

Conditions

Postpartum Hemorrhage Prevention by Using Oxytocin Verses Misoprostol

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Women with aheathy singleton pregnancy in spontaneous or induced labor at term . Exclusion Criteria: * Hypersensitivity/Contraindication to prostaglandins Antepartum hemorrhage Multiple pregnancy Cardiac disease Malpresentation Rhesus- negative mother hypersensitive disorders Severe anaemia(hemoglobin\<7g/dl)

Locations (1)

AinShamsU

Cairo, Egypt

Outcomes

Primary Outcomes

reduce blood loss during third and fourth stages of labor.

reduce blood loss during third and fourth stages of labor by using misopristol is better than using oxytocin

Time frame: 1 year

Secondary Outcomes

the duration of the third stage of labor ,need for oxytocics ,blood transfusion and any adverse effects of the drugs

the duration of the third stage of labor ,needed for oxytocics ,blood transfusion and any adverse effects of the drug will be reduced with mesopristol

Time frame: 1 year

Central Contacts

Rasha mohamed, M.B;B.CH

CONTACT

abosalma_82@yahoo.com

Data from ClinicalTrials.gov

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