Comparison of Synchrony Between 4 NIV Ventilators

University of Lausanne Hospitals22 enrolled

Overview

Comparison of the effects of 4 ventilators dedicated to NIV (2 home ventilators and 2 ventilators designed for NIV) on patient-ventilator synchrony and comfort in patients admitted in the intensive care unit for respiratory failure and treated with NIV.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Respiratoy Failure Requiring NIV Treatment

Interventions

V-PAP III ventilatorDEVICE

Stellar 150 ventilatorDEVICE

BiPAP vision ventilatorDEVICE

V60 ventilatorDEVICE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * respiratory failure Exclusion Criteria: * Severe hypoxemia requiring an FiO2 \> 0.6 * Hemodynamic instability : defined as a variation of \> 20% in mean arterial pressure (MAP) and heart rate (HR) during the previous 2 hours; the need for high doses of catecholamines (namely \> 0.5 mcg/kg/min) and/or the need of major volume resuscitation (more than 2 liters of fluids in 2 hours) * Impaired consciousness or absence of patient cooperation; * Facial or laryngeal lesions contraindicating the use of NIV; * Poor short term prognosis. * Age \< 18 years old

Locations (1)

Intensive care and burn unit / CHUV

Lausanne, Canton of Vaud, Switzerland

Outcomes

Primary Outcomes

Patient-ventilator synchrony

Patient-ventilator synchrony will be assessed breath by brath on the basis of airway pressure, flow and diaphragmatic electrical activity recordings.

Secondary Outcomes

comfort of patient under NIV

Patient's confort during NIV will be assessed using a visual analogic scale.

Ventilatory parameters

Tidal volume, respiratory rate, inspiratory time, expiratory time and maximal and mean airway pressure will be measured from the continuous recording of airway pressure and flow.

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.