Assessment of Hemodynamic Response in Cardiopulmonary Bypass Graft After Cardiopulmonary Bypass Using Transesophegeal Echocardiography

Federal University of Juiz de Fora81 enrolled

Overview

This is a double blind randomization study, assessing hemodynamic response in patients who underwent a cardiopulmonary bypass graft (CABG) with cardiopulmonary bypass (CPB) using intraoperative trasnesophageal echocardiography (TEE) to know what inotropic drug will be batter to improve the heart function. Epinephrine, milrinone, dobutamine and levosimendan will be assessment.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Cardiopulmonary Bypass Graft

Interventions

epinephrine and levosimendanDRUG

epinephrine (0,06mcg/kg/min), levosimendan (0,2 mcg/kg/min)

Eligibility

Sex: ALLMin age: 45 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Sinusal ritmus * EF \> 35% * Elective CABG surgery Exclusion Criteria: * No accept * Severe valvular regurgitation or stenoses * Chest pain * Cardiogenic shock

Locations (1)

National Institute of Cardiology / Ministry of Health

Rio de Janeiro, Rio de Janeiro, Brazil

Outcomes

Primary Outcomes

Systolic and diastolic heart function

Assessment the systolic and diastolic heart function

Time frame: Two years

Secondary Outcomes

Mortality after CABAG

Assessment mortality after CABAG

Time frame: Two years

Data from ClinicalTrials.gov

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