Cortical Organization in Allogeneic Transplants or Heterotopic Hand Replants

Christine M. Kleinert Institute for Hand and Microsurgery60 enrolled

Overview

The investigators hope to gain insights into the functional organization of the human cerebral cortex in response to upper limb amputation and surgical interventions including hand replantation and hand transplantation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Hand Transplant Hand Replant

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * between 18-70 yrs old * undergone successful allogeneic transplantation of one or both hands OR undergone successful reattachment of one or both hands OR will have experienced surgical repair of one or more severed nerves (ulnar, medial, radial, digital in the upper limb * must speak English Exclusion Criteria: * younger than 18 years or older than 70 years * not undergone a replant or transplant

Locations (1)

Christine M. Kleinert Insitute of Hand and Microsurgery

Louisville, Kentucky, United States

RECRUITING

Outcomes

Primary Outcomes

Ultrasound Biomicroscopy

We will scan the cross section of the medial nerve at the pisiform bone level to determine the level of CTS with Ultrasound Biomicroscopy machine. This device is not approved for clinical decisions, only used for research purposes.

Time frame: Up to 12 months

Secondary Outcomes

Grip Strength

Time frame: Up to 12 months

Pinch Strength

Time frame: Up to 12 months

DASH Questionnaire

Subjects will complete the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire.

Time frame: Up to 12 months

Central Contacts

Christina L Kaufman, PhD

CONTACT

502-562-0390 ckaufman@cmki.org

Donna Stacy, RN, MSN

CONTACT

502-562-0313 dstacy@cmki.org

Data from ClinicalTrials.gov

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