This trial is conducted in Europe. The aim of this trial is to investigate whether the volume of water administered with NN9924 affects the anatomical location (stomach or proximal small bowel) of tablet erosion.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
27
Subjects will be treated with two single doses of 10 mg semaglutide in a tablet. Dosing will be done on 2 dosing visits separated by 4 to 6 weeks.
Unnamed facility
Nottingham, United Kingdom
Anatomical location (stomach or proximal small bowel) of tablet at complete tablet erosion (CTE)
Time frame: Assessed 0-4 hours post dose
Area under the NN9924 concentration curve
Time frame: From time 0-24 hours
Anatomical location of initial tablet erosion (ITE)
Time frame: Assessed 0-4 hours post dose
Time to ITE
Time frame: Assessed 0-4 hours post dose
Time to CTE
Time frame: Assessed 0-4 hours post dose
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