The purpose of this study is to determine whether different clonidine concentration on axillary brachial plexus block with 1,5% lidocaine for upper limb surgery may influence the sensory and motor block onset time and duration, postoperative analgesia duration, postoperative pain intensity
Brachial plexus blocks are frequently used in surgical procedures involving the upper limb because they facilitate surgical anaesthesia, muscle relaxation and post-operative analgesics. Various drugs are used to supplement local anaesthetics during brachial plexus block. Many studies in the literature show that clonidine, which is an alpha-2 agonist, prolongs the length of anesthesia and post-operative analgesia.4,5 However, clonidine's side effects-such as hypotension, bradycardia and sedation can limit its use. There are no studies comparing different clonidine concentrations on the axillary brachial block, so the hypothesis of the present study was that different clonidine concentrations and LA volumes may influence the anaesthesia and analgesia quality on this type of regional block.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
Clonidine 1 ml - 150 mcg on 20 ml de lidocaine 1,5% on axillary brachial plexus block for upper limb surgery
Clonidine 1 ml - 150 mcg on 40 ml of lidocaine 1,5% - single injection on axillary brachial plexus block for upper limb
Lidocaine 1,5% 20 ml 300 mg for single injection on axillary brachial plexus block for upper lim surgery
sensorial and motor block duration
to compare two concentrations of clonidine on different volumes of lidocaine, in terms of sensorial and motor block duration
Time frame: 24 hours after surgery
adverse effects of additive clonidine on axillary brachial plexus block in upper limb surgery
analyse the adverse effects of additive clonidine on axillary brachial plexus block in upper limb surgery
Time frame: 24 hours after surgery
postoperative analgesia duration
to compare two concentrations of clonidine on different volumes of lidocaine, in terms of postoperative analgesia duration
Time frame: 24 hours
sensorial and motor block onset time
to compare two concentrations of clonidine on different volumes of lidocaine, in terms of sensorial and motor block onset time
Time frame: 24 hours
postoperative pain intensity
to compare two concentrations of clonidine on different volumes of lidocaine, in terms postoperative pain intensity
Time frame: 24 hours
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Lidocaine 40 ml 1,5% 600 mg single injection for axillary brachial plexus block for upper limb surgery