To compare postoperative pain, opioid consumption and chronic pain in patients undergoing to hernia repair surgery after receiving nitrous oxide or oxygen during the general anesthesia.
The study is prospective and double blind. In the clinic, patients undergoing inguinal hernia surgery that meet the criteria for inclusion into the study and agreed to participate in the study will be randomized into two groups. In the first group of patients will receive Nitrous Oxide and In the second group of patients will receive oxygen during the general anesthesia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Nitrous Oxide, 70%, O2 30%) 1-5 L, Sevoflurane 1-2%, ETCO2: 32-35 mmHg.
Subjects will receive General anesthesia: (Air, 70%, O2 30%) 1-5 L, Sevoflurane 1-2%, ETCO2: 32-35 mmHg.
Gulhane Military Medical Academy Hospital
Etlik, Ankara, Turkey (Türkiye)
Nitrous oxide and chronic pain
The effect of 70% N20/30% O2 on post inguinal hernia repair procedure in prevention of chronic pain.
Time frame: 30 days post operative
Nitrous oxide and opioid consumption
The effect of 70% N20/30% O2 on post inguinal hernia repair procedure in decrease in opioid consumption.
Time frame: 4 hours after surgery
smoking and post operative pain
The effect of active smoking to increase post operative acute pain.
Time frame: 4 hours after surgery
smoking and chronic pain
The effect of active smoking and chronic pain
Time frame: 30 days post operative
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