Self-directed Titrated Transdermal Nicotine Patch Versus Standard Treatment for Smoking Cessation

Inclusion Criteria: 1. Current smoker (≥ 10 cigarette per day); 2. 18 years of age or older; 3. Willing to set a date to quit smoking within the 30 days following the baseline assessment; 4. Participant is willing to return to the UOHI for follow-up examination; 5. Participant is willing to provide informed consent; 6. Motivated to quit smoking. Exclusion Criteria: 1. Participant is unable to read and understand English or French; 2. Participant is pregnant, lactating or planning to become pregnant during the study period; 3. Participant has attempted to quit smoking in the previous month with the support of medication for \>72 hours; 4. Participant is currently using a smoking cessation medication (e.g., NRT, Bupropion, Varenicline,Clonadine, Notriptyline); 5. Participant has contraindication(s) to nicotine replacement therapy (allergy to adhesive, life-threatening arrhythmias (e.g., tachycardia); 6. Participant is during the immediate post-myocardial infarction period (i.e. incident has occurred within the last 10 days); 7. Severe or worsening angina pectoris; 8. Subject has had a recent cerebral vascular accident (i.e. incident has occurred within the last 10 days); 9. Participant currently suffering with depression (BDI-II ≥20); 10. Participant who has been diagnosed with depression or treated with an antidepressant in the past 12 months; 11. Past or present history of psychosis (Schizophrenia, Schizophreniform or Delusional Disorders),panic disorder, or bipolar disorder; 12. Drug or alcohol abuse or dependence in the past year; 13. Member of the participant's household is already participating in the study or in the "Quit Smoking in the 'Real World'" study; 14. Participant is currently participating in or already receiving counseling or follow-up for smoking cessation. 13.) Participants who in the opinion of the investigator will be unlikely to commit to a year-long study;