Epigenetic Modifications of Diabetes Mellitus Type I

Scripps Translational Science Institute

Overview

This research is being done to find out if significant changes in blood glucose cause bad outcomes in patients with diabetes.

Study Type

OBSERVATIONAL

Conditions

Type I Diabetes

Interventions

Oral glucose tolerance test for Phase IPROCEDURE

Oral glucose tolerance test for Diabetic patients in phase I

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 18-65 years old * Diagnosis of Type I diabetes * Willing to wear continuous blood glucose monitor as specified in protocol Exclusion Criteria: * Pregnant or planning to become pregnant during the study Healthy control group Inclusion: * 18-65 years old * Willing to wear continuous blood glucose monitor as specified in protocol Exclusion: * Pregnant or planning to become pregnant during the study * Diagnosis of Type I or II Diabetes

Locations (1)

Scripps

San Diego, California, United States

Outcomes

Primary Outcomes

Evaluate blood sugar variability in Type I diabetics for differences in epigenetic signatures between Type I diabetics with little glycemic variability as compared to those with more pronounced glycemic changes.

Time frame: 7 days

Data from ClinicalTrials.gov

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