A Study to Assess Dose-Response, Efficacy (Immunogenicity) and the Safety of GC1109

Step1 Inclusion Criteria: * Healthy 18 to 55 year-olds of either sex * Body mass index above 18.5kg/m2 or below 30kg/m2 at the screening time * A medical history without clinically significant congenital or chronic disease at the screening test before administrating the study drug within 28 days * Agreement to avoid pregnancy or use contraceptive measure between 1 week prior to first dose and the 4 weeks following the final administration * Female subjects of childbearing age, have negative serum β-HCG prior to infuse the study drug within 7 days and urine test at the every pre-vaccine * Signed, informed voluntarily consents the clinical trials * Willingness and agreement to comply with the constraints of the study protocol and ability to understand the study * Willingness and ability to return for all follow-up visits and blood draws for the duration of the study * Subjects who can have the study vaccine administered into the deltoid muscle and don't have the tattoo * Agreement to stop drinking for 7days following the administration of the each study vaccine * Agreement not to donate the blood for 24 hours following the administration of the each study vaccine Exclusion Criteria: * Prior history of, or known exposure to any form of B.anthracis or any anthrax immunization * Employment in an industry involved in contact with ruminant animals, slaughterhose workers, handle the animal raw hides or raw wool, veterinary sciences involving ruminant animals, suspect exposure to any form of B. or anthrax immunization producer and developer. * HIV positive or syphilis HAV, HBV, HCV positive or suspect * Clinically significant out-of-range of laboratory tests at screening including : hypernatremia, hyponatremia, hypopotassemia, hyperchloremia, hypoproteinemia * Prior history of, immunodeficiency or clinically active autoimmune disease * Subjects with a history of Guillain-Barre syndrome * Subjects with hemophilia or being treated with an anticoagulant who are at increased risk of serious bleeding during intramuscular injection * History or evidence of metastatic malignancy tumor for internal organs, blood or flesh * Medical significant hypersensitivity or idiosyncratic reaction related to any medical product including study drug or with a history of anaphylaxis * Subjects who have had an acute fever exceeding a body temperature of 38.0℃ within 72 hours prior to the administration of the study vaccine, or who have had a symptom suspicious for acute febrile disease within 14 days prior to the administration of the study vaccine. * Individuals who have received or intend to receive medication within 30 days of injection of the any experimental drug * Donation of blood within 30 days prior to administrate the study drug * Subjects who have received or are scheduled for the treatment with the following drug within 120 days (except for inhaled, nasal or topical corticosteroid) * Subjects who have received or are scheduled for the treatment with the following drug within 120 days (except for inhaled, nasal or topical corticosteroid) * Systemic immunosuppressant therapy, radiotherapy, a high dose of steroid at the similar dose level * Blood-derived products including immunoglobulin * Systemic immunosuppressant therapy, radiotherapy, a high dose of steroid at the similar dose level Blood-derived products including immunoglobulin * Subjects who have received or are scheduled for the treatment with the following drug within the specified period * Pre-injection of the IP within 30 days: oriental medicine * Pre-injection of the IP within 7 days: ethical the counter drug (ETC), over the counter * History or suspect of drug abuse (Amphetamine, barbiturates, cocaine, opioids, benzodiazepines etc) * Subject without safety for the administration of vaccine, who in the investigator's opinion are unsuitable for the study or disturb the assessment of clinical trials Step2 Inclusion Criteria: * Healthy 19 to 65 year-olds of either sex * A medical history without clinically significant congenital or chronic disease at the screening test before administrating the study drug within 28 days. * For woman of childbearing age who have not undergone sterilization operation and woman who have not been more than 12 months after menopause, those who agree to avoid pregnancy or use appropriate contraceptive measure for the duration of the study from within one week prior to the first clinical drug administration. Man, who agree to avoid pregnancy or use contraceptive measure for the duration of the study * Female subjects of childbearing age, have negative in pregnancy test at the screening visit * Signed, informed voluntarily consents the clinical trials * Subjects who can have the study drug administered into the deltoid muscle and don't have the tattoo * Agreement not to donate the blood for the duration of the study Exclusion Criteria: * Prior history of, or known exposure to any form of B. anthracis or any anthrax immunization * Employees in an industry involved in contact with ruminant animals(slaughterhouse workers, handle the animal raw hides or raw wool, veterinary sciences involving ruminant animals, suspect exposure to any form of B. or anthrax), immunization producer and developer. * HIV positive or suspect * HAV, HBV, HCV positive or suspect * Prior history of, immunodeficiency or clinically active autoimmune disease * Subjects with a history of Guillain-Barre syndrome * Subjects with hemophilia or being treated with an anticoagulant who are at increased risk of serious bleeding during intramuscular injection * History or evidence of metastatic malignancy tumor for internal organs, blood or flesh * Medical significant hypersensitivity, idiosyncratic reaction related to any medical product included in study drug or with a history of anaphylaxis * Subjects who have had an acute fever exceeding a body temperature of 38.0℃ within 72 hours prior to the administration of the study vaccine, or who have had a symptom suspicious for acute febrile disease within 14 days prior to the administration of the study drug. * A person who has received a split vaccine, inactivated vaccine, or actived vaccine within four weeks prior to administration of a study drug * Subjects who have received or are scheduled for the treatment with the following drug within 120 days (except for inhaled, nasal or topical corticosteroid) * Systemic immunosuppressant therapy, radiotherapy, a high dose of steroid at the similar dose level * Blood-derived products including immunoglobulin * A person who has a history of drug abuse within 6 months prior to the administration of a study drug or suspected of taking drugs for fear of abuse through questionnaire and physical examination * Pregnant women and lactating women * A person whom the investigator determined unsuitable for the study