Mesenchymal Stem Cells; Donor and Role in Management and Reconstruction of Nonunion Fracture

Indonesia University10 enrolled

Overview

The investigators hypothesized that mesenchymal stem cells can be isolated from fracture site, iliac crest, and tibial crest, and can be expanded to be used in the management of nonunion fracture.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Healing of Fracture

Interventions

stem cells + hydroxy apatiteDRUG

patient will be transplanted with stem cells and hydroxyapatite

autograft taken from iliac crestOTHER

patient will be transplanted with autograft

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: * athropic nonunion fracture of the long bone Exclusion Criteria: * immunocompromise, * active infection, * pathological fracture, * ongoing hormonal therapy

Locations (1)

RSCM

Jakarta, Indonesia

RECRUITING

Outcomes

Primary Outcomes

healing of fracture

radiological union

Time frame: 1 year

Secondary Outcomes

VAS

visual analogue scale

Time frame: 1 year

Central Contacts

Phedy Phe, MD

CONTACT

phedy@yahoo.com

Ismail HD, PhD

CONTACT

phedy2@yahoo.com

Data from ClinicalTrials.gov

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