Evaluation of Finastride Effect in Different Dosage on the Amount of Perioperative Bleeding in Transurthral Resection of Prostate

Shiraz University of Medical Sciences60 enrolled

Overview

Preoperative use of finastride will decrease the amount of perioperative blood loss during and after TURP The effect of finastride on decreasing the amount of perioperative blood loss during and after TURP is dose dependent Finastride will decrease microvascular density in prostate tissue and this effect is dose dependent

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Benign Prostate Hyperplasia

Interventions

TURPPROCEDURE

Transurthral resection of prostate

Eligibility

Sex: MALEMin age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with BPH that require TURP Exclusion Criteria: * Previous prostate surgery * Prostate Cancer * Coagulopathy * The use of NSAIDs, Anticoagulants, Antiplatelet drugs * CRF/ESRD

Locations (1)

Faghihi Hospital

Shiraz, Fars, Iran

Outcomes

Primary Outcomes

Perioperative Hb Drop

Time frame: 24 hours after surgery

Data from ClinicalTrials.gov

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