The investigators are trying to evaluate the performance of neutrophil and lymphocyte counts as a risk factor of deep sternal wound infection after coronary artery bypass graft surgery.
Deep sternal wound infection after coronary artery bypass graft is a very dangerous complication as it prolongs hospital stay, increase morbidity and mortality, and increase cost of care. As a risk factor of surgical site infection, risk index reported by NNIS (national nosocomial infection surveillance), Euroscore, or Society of thoracic surgeon risk score are currently used. However, as various performances are reported regarding these index or scoring systems, and many factors are needed for these index or scoring system, there is a need to develop a more simple risk factor with better performance. We focused on the differential blood cell count, as the neutrophil and lymphocyte count are related to the degree of surgical invasion, and inflammatory response. Previous studies reported that the neutrophilia or lymphopenia is related to postoperative infection. Therefore, we are trying to evaluate the performance of preoperative or postoperative the blood cell differential count as a risk factor for sternal wound infection after coronary artery bypass surgery.
Study Type
OBSERVATIONAL
Enrollment
1,850
Samsung Medical Center
Seoul, South Korea
RECRUITINGpostoperative surgical wound infection
postoperative surgical wound infection within first week after the end of coronary artery bypass graft surgery, classified as a superfical or deep sternal wound infection
Time frame: within first week after the end of coronary artery bypass graft surgery
preoperative total leukocyte count
preoperative total leukocyte count
Time frame: 1 day before surgery
preoperative neutrophil count
preoperative neutrophil count
Time frame: 1 day before surgery
preoperative lymphocyte count
preoperative lymphocyte count
Time frame: 1 day before surgery
postoperative total leukocyte count
postoprative total leukocyte count
Time frame: 2 hour after the end of surgery
postoperative neutrophil count
postoperative neutrophil count
Time frame: 2 hour after the end of surgery
postoperative lymphocyte count
postoperative lymphocyte count
Time frame: 2 hour after the end of surgery
preoperative NNIS risk index
preoperative NNIS risk index
Time frame: 1 day before surgery
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preoperative EuroScore
preoperative EuroScore
Time frame: 1 day before surgery
Preoperative STS
Preoperative STS (Society of Thoracic Surgeons risk score)
Time frame: 1 day before surgery
the incidence of surgical reopen with surgical wound infection
the incidence of surgical reopen with surgical wound infection
Time frame: within 1 month after surgery