Catheter related infection is the third cause of nosocomial infection in ICUs. Most of them are avoidable and can be prevent by improving aseptic practices during catheter insertion and maintenance. Indeed, the main route of catheter contamination for short-term catheters is the insertion site. Consequently, the quality of skin disinfection is the most effective preventive measure to reduce the incidence of these infections. This aim of the present study is to compare four strategies of skin disinfection to determine whether a 2% alcoholic solution of chlorhexidine acts better than 5% alcoholic povidone iodine in reducing catheter infection and to assess whether a detersion phase prior to disinfection reduces catheter colonization as compared with no detersion.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
2,400
Angers University Hospital
Angers, France
Estain University Hospital
Clermont-Ferrand, France
Bichat-Claude Bernard Hospital
Paris, France
Lyon University Hospital
Pierre-Bénite, France
Poitiers University Hospital
Poitiers, France
Major catheter related infection
Catheter colonization
Catheter related bacteremia
Colonization insertion site
Prolongation hospitalization due to catheter infection
Mortality due to catheter infection
Skin allergy and anaphylactic shock
Costs
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