The purpose of this study is to determine whether levothyroxine is effective and safe in the treatment of children with euthyroid sick syndrome, hospitalized in a pediatric intensive care unit.
Children with euthyroid sick syndrome, hospitalized in a pediatric intensive care unit, will be randomised to receive either Levothyroxine or placebo, to determine if it diminishes mortality.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
80
3 mcg/kg/day
Placebo.
Sinaloa Pediatric Hospital
Culiacán, Sinaloa, Mexico
All cause mortality
Time frame: participants will be followed for the duration of hospital stay, an expected average of 3 weeks
Length of time in intensive care
Time frame: participants will be followed for the duration of hospital stay, an expected average of 2 weeks
Ventilation days
Time frame: participants will be followed for the duration of hospital stay, an expected average of 2 weeks
Use of vasopressors
Time frame: participants will be followed for the duration of hospital stay, an expected average of 3 weeks
Thyroid hormones levels
Time frame: participants will be followed for the duration of hospital stay, an expected average of 3 weeks
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