A Comparison of microRNA Samples in Patients With Nasal Polyps and Aspirin Exacerbated Respiratory Disease and Those With Nasal Polyps Only

Inclusion Criteria: * Ages eligible for study: 18 to 70 years * Genders eligible for study: male and female * Signed and dated written informed consent is obtained prior to study * Subjects have a physician diagnosis of nasal polyps without AERD or physician diagnosis of nasal polyps with AERD. The diagnosis of aspirin sensitive asthma must be present for a minimum of three months. If the medical history is indeterminate either an aspirin challenge will be required to confirm or rule out the diagnosis. An aspirin challenge is a protocol that can safely be performed as an out patient procedure with close supervision. Exclusion Criteria: * Pregnant and/or lactating females. * Current tobacco use. * Severe psychiatric illness. * Current illicit substance use or dependence and/or abuse of alcohol. * Primary or secondary immunodeficiency. * Any clinically significant uncontrolled medical condition that would put the patient at risk.