The aim of this study is to evaluate the clinical performance on Analgesia/Nociception Index (ANI) in the assessment of immediate postoperative analgesia in PACU in adult patients undergoing general anesthesia.
Evaluation of the relationship between ANI and numerical rating pain scale (NRS) by linear regression. Assessment of the performance of ANI to detect NRS\>3 and NRS\>=7 by building ROC curves.
Study Type
OBSERVATIONAL
Enrollment
200
Department of Anesthesiology and Intensive Care, Édouard Herriot hospital, HCL
Lyon, France
Analgesia/Nociception Index (ANI)
The ANI is a 0-100 index estimating the parasympathetic/sympathetic balance derived from heart rate variability, measured by the PhysioDoloris monitor (MetroDoloris, Loos, France). High ANI values indicate parasympathetic predominance (no pain) while during nociception (increase in sympathetic activity), ANI value decrease to 60 or less.
Time frame: At arrival in post-operative care unit (PACU) or 10 min after extubation
Pain Scores on a 0-10 Numeric Rating Scale (NRS)
Verbal pain scale, with 0 = no pain and 10 = worst pain imaginable. NRS\<3 corresponds to no or mild pain NRS\>=3 corresponds to moderate to severe pain NRS\>=7 corresponds to severe pain
Time frame: At arrival in PACU or 10 min after extubation
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