NT-proBNP as a Tool for the Detection of Acute Pulmonary Artery Embolism (APE)

University of Ulm44 enrolled

Overview

In patients with suspected APE (Acute Pulmonary Embolism) referred to the intensive care unit (ICU)after major surgery, serum NT-proBNP (N-terminal proBNP), Troponin-I and D-dimers were measured according to the standard hospital protocol. To definitively confirm or exclude APE, all patients underwent an angiographic CT-scan of the thorax.

In patients with suspected APE referred to the intensive care unit after major surgery, serum NT-proBNP, Troponin-I and D-dimers were measured according to the standard hospital protocol. Blood samples were obtained within one hour after the onset of clinical symptoms. Definitive confirmation or exclusion of APE was performed with an angiographic CT-scan of the thorax.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pulmonary Embolism Pulmonary Embolism Without Mention of Acute Cor Pulmonale

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: all patients referred to the ICU with suspected APE Exclusion Criteria: none

Locations (1)

University of Ulm, Michelsberg anaesthesiologic ICU

Ulm, Baden-Wurttemberg, Germany

Outcomes

Primary Outcomes

Acute pulmonary embolism: CT-proof yes vs. no

Time frame: 1 hour after onset of clinical symptoms

Data from ClinicalTrials.gov

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