Bicarbonates Versus Saline for Contrast Induced Acute Kidney Injury Prevention in Intensive Care Unit

University Hospital, Caen300 enrolled

Overview

The aim of this study is to compare bicarbonates versus saline for prevention of contrast induced acute kidney injury in critically ill patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

300

Conditions

Contrast Induced Acute Kidney Injury

Interventions

bicarbonatesDRUG

sodium bicarbonates 1,4%

salineDRUG

sodium chloride 0,9%

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patient \> 18 years old * in intensive care unit since 24h and for up to 48 hours * with contrast medium injection Exclusion Criteria: * patient under renal replacement therapy * rise in creatinine \> 26µmol/L within 48hours * anuria within 12 hours * cardiogenic pulmonary oedema * pH \> 7.50 or kaliemia \< 3mmol/L * pregnancy

Locations (3)

Medical Intensive Care Unit

Caen, France

Surgical Intensive Care Unit

Caen, France

Intensive care unit

Saint-Lô, France

Outcomes

Primary Outcomes

contrast induced acute kidney injury

Time frame: 72 hours

Data from ClinicalTrials.gov

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