The purpose of the study is to assess the efficacy of a new serotonin-norepinephrine reuptake inhibitor (SNRI) nin functional recovery after ischemic stroke.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
532
Percentage of patients with a Modified Rankin Scale (mRS) less than or equal to 1 at Week 12
Time frame: week 12
Percentage of patients with NIHSS score less than or equal to 5 at Week 12
Time frame: week 12
Percentage of patients with at least one moderate to severe depressive
Time frame: Baseline to week 12
Change from baseline to Week 12 of the mean NIHSS total and motor scores
Time frame: baseline to week 12
Safety and tolerability assessed by the investigator including SAEs, AEs, vital signs, ECG,physical examination and laboratory tests
Time frame: baseline to week 12
Percentage of patients with a mRS score less than or equal to 2 at Week 12
Time frame: baseline to week 12
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Brno, Czechia
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...and 77 more locations