Flare Measurements in Human Radiation Therapy Patients

ChromoLogic, LLC10 enrolled

Overview

This is a longitudinal Feasibility Study of a novel non-invasive device in assessing radiation dose exposure in humans. All patients receiving whole body irradiation therapy and meeting all other inclusion/exclusion criteria will receive ocular flare meter measurements and slit-lamp examinations on up to eleven occasions starting prior to the first fractional dose of irradiation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

The Impact of Whole Body Irradiation on Ocular Flare

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects must be scheduled to receive whole body irradiation in a dose range from 1.5 to 12Gy. * Subjects must not have received ocular surgery for at least three months prior to study enrolment. * Subjects must not have a history of uveitis. * Subjects must have at least one eye free of cataracts * Subject age must be greater than 18 years * Subjects must have the ability to understand and willingness to sign a written informed consent document. Exclusion Criteria: * Inability to give informed consent * Cataracts in both eyes * Subject has received ocular surgery within the prior three months * Subject has a history of uveitis

Locations (1)

UCLA Radiation Oncology

Los Angeles, California, United States

Outcomes

Primary Outcomes

Ocular flare in radiotherapy patients

Determine if ocular flare meter spectra and/or a slit-lamp eye exam can assess radiation dose exposure in individual human radiotherapy patients.

Time frame: Daily measurements for the duration of radiotherapy treatment (expected up to four days from start of treatment)

Data from ClinicalTrials.gov

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