The study will use a comprehensive behavioral intervention adapted for pregnant women to change dietary intake, eating behavior and physical activity. The central hypothesis of this study is that the intervention will reduce excess gestational weight gain and achieve clinical and metabolic benefits in obese and overweight pregnant women and their infants over the first year of life.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
50
Intervention includes meetings with a nutrition counselor and/or psychologist where individualized eating plans will be developed and reviewed, and regular group meetings during which information about healthy eating for weight management will be discussed.
Tufts Medical Center
Boston, Massachusetts, United States
Tufts University Human Nutrition Research Center on Aging
Boston, Massachusetts, United States
Maternal and Infant Body Weight Change
* Maternal non-fasting weight measured at all prenatal clinic and study visits. * Infant weight measured at birth and all pediatric clinic visits through 1 year.
Time frame: From first trimester through 1 year post-partum
Infant Outcomes
* Body composition (i.e. length, head circumference, skinfold thickness, waist circumference) changes through the first year. * Characteristics at birth including Apgar score, gestational age. * Dietary intake and food preferences at 1 year.
Time frame: From birth through first year
Maternal and Perinatal Outcomes
* Rates of cesarean delivery, gestational hypertension/preeclampsia, preterm birth, birth complications. * Fasting blood glucose and insulin concentrations throughout pregnancy. * Body composition and energy requirements at baseline and 24-28 weeks of pregnancy. * Total energy expenditure at 24-28 weeks of pregnancy. * Rate of breastfeeding and breastfeeding practices at 1, 3, 6, and 12 months post-partum.
Time frame: First trimester through 1 year post-partum
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