Plasma Levels of GDF-9 and GDF-15 in Patients With Polycystic Ovary Syndrome.

Inclusion Criteria: * Female patients at ages 25-35 diagnosed with polycystic ovarian syndrome and idiopathic hirsutism Exclusion Criteria: * acute infectious disease, a thyroid, pituitary, nutritional, inflammatory, hepatic, renal, or neoplastic disorder; history of cardiovascular disease or pulmonary embolism; a family history of coronary artery disease; smoking history; hypertension; diabetes mellitus; use of oral contraceptives, anti-androgens and drugs known to interfere with cytokine release, such as corticosteroids, immunosuppressors, or nonsteroidal antiinflammatory drugs. any medication known to affect hormonal or metabolic parameters.