Effect of Hyoscine and Promethazine on Labor Pain

Mashhad University of Medical Sciences93 enrolled

Overview

It is always considered to shorten the duration of delivery without compromising the mother and fetus by obstetrics. Hyoscine and Promethazine are used widely in hospital and research is very limited, with conflicting results regarding the efficacy of these two drugs. So the investigators decided to compare of effect of hyoscine N-butyl bromide and Promethazine on length of active phase of the first stage of labor.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

DOUBLE

Enrollment

Conditions

Labor Pain

Interventions

HyoscineDRUG

The samples were randomly allocated to inject of 20 mg of hyoscineIM in dilatation 3-5cm.

PromethazineDRUG

The samples were randomly allocated to inject of 25 mg of promethazine IM in dilatation 3-5cm.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 18-35 yrs, * primiparous, * having single fetus with cephalic presentation, gestational age 37-42 weeks, * having no medical diseases, * having no history of hospitalization due to psychological diseases, * having no addiction to cigarette, * having no complications during pregnancy such as hypertension, * BMI\< 26 Exclusion Criteria: * bleeding * CPD * use of PG or Oxytocin * fetus distress

Outcomes

Primary Outcomes

Effect of Hyoscine and Promethazine on labor pain

Time frame: up to 9 months

Data from ClinicalTrials.gov

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