Specific policies on obesity reduction often include a recommendation to reduce sugar consumption as a means of lowering overall caloric intake. Reformulating processed foods (e.g. sugary products) is considered one of the key options for improving population diet. The implications of regular consumption of reformulated products are not fully understood. Previous studies have demonstrated that dietary compensation is common, although the extent is not fully elucidated. In addition to the perceived impact of sugar consumption on weight control, high sugar intake, specifically sucrose and fructose, has been implicated in the increase of plasma lipids and markers of insulin resistance. However to date no randomised controlled study has investigated whether the consumption of reformulated low sugar products as components of a habitual diet have a significant impact on plasma lipid, insulin or glucose concentrations within a free-living, non-diseased population. It is hypothesised that exchange of reformulated, low sugar food products for habitually consumed foods will result in dietary compensation and minimal weight change compared with unmodified products and will have little impact on plasma glucose, insulin and lipid levels.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
50
Subjects were asked to supplement their habitual diet with reformulated sugar-reduced products for 8 weeks. Subjects were provided with reformulated beverages, sauces, condiments and snacks. They were asked to consume a minimum of 1 drink + 1 food portion intervention supplement daily, in exchange for habitually eaten equivalent foods.
Subjects were asked to supplement their habitual diet with conventional sugar products for 8 weeks. Subjects were provided with conventional beverages, sauces, condiments and snacks. They were asked to consume a minimum of 1 drink + 1 food portion intervention supplement daily, in exchange for habitually eaten equivalent foods.
Department of Food and Nutritional Sciences, University of Reading
Reading, Berks, United Kingdom
Changes in body weight and body composition
Time frame: 20 weeks. Baseline and week 8 assessments for two dietary intervention arms
Changes in energy and nutrient intake
Time frame: 20 weeks. Run-in period and week 7 assessments for two dietary intervention arms
Changes in appetite and mood ratings
Subjective sensations of appetite and mood by visual analogue scale
Time frame: 20 weeks. Run-in period and week 7 assessments for two dietary intervention arms
Changes in physical activity levels
Measured by accelerometry
Time frame: 20 weeks. Run-in period and week 7 assessments for two dietary intervention arms
Changes in fasting plasma lipid, insulin and glucose concentrations
Time frame: 20 weeks. Baseline and week 8 assessments for two dietary intervention arms
Changes in vascular stiffness by pulse wave analysis (PWA) and digital volume pulse (DVP)
Time frame: 20 weeks. Baseline and week 8 assessments for two dietary intervention arms
Changes in cardiovascular risk factors (blood pressure, inflammatory markers)
Time frame: 20 weeks. Baseline and week 8 assessments for two dietary intervention arms
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