The purpose of this study is to understand how differences in the nutritional status and concentration of hormones and cytokines associated with cachexia in HIV+ and HIV- pregnant women living in a semi-rural and rural region of northern Tanzania affect fetal growth, pregnancy outcomes and early infant health and development. The study hypothesis is that HIV+ women will have worse nutritional status and a greater degree of cachexia which will negatively impact fetal growth, pregnancy outcomes and early infancy health and development.
Study Type
OBSERVATIONAL
Enrollment
218
Kisesa Health Centre
Kisesa, Tanzania
Maternal cachexia score
Time frame: Up to 1 month post-partum
Maternal anthropometric measures
weight, height, mid-upper arm circumference, triceps skinfold, fundal height
Time frame: Up to 1 month post-partum
Fetal growth
Time frame: Up to 1 month post-partum
Pregnancy outcomes
spontaneous abortion, stillbirth, preterm delivery, perinatal mortality (death within first 7 days), neonatal mortality (death within first 28 days), small for gestational age, intrauterine growth retardation, low birth weight
Time frame: Up to 1 month post-partum
Early infant anthropometrics
weight, length, head circumference, mid-upper arm circumference, triceps skinfold
Time frame: Up to 1 month post-partum
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