Genetic Load and Phenotype in Aggressive AMD

Inclusion Criteria: * Subject is male or female 50 years of age and older * Subject provides a signed and dated informed consent * Subject agrees to provide two buccal swabs in accordance with this protocol * Diagnosis of CNV secondary to AMD in at least one eye Exclusion Criteria: * Previous sample donation under this protocol * Presence of retinal disease involving the photoreceptors and/or outer retinal layers other than AMD loss such as high myopia, retinal dystrophies, central serous retinopathy, vein occlusion, diabetic retinopathy and uveitis or similar outer retinal diseases which have been present prior to the age of 50. * Opacities of the ocular media, limitations of pupillary dilation or other problems sufficient to preclude adequate imaging of the posterior segment.