There is no objective evidence of how long intravenous solutions remain inside venous blood vessels after they have been administered, therefore there is no definite guideline of how to administer them in the preoperative setting. Besides, obese patients represent a particular group of subjects as they theoretically with-hold a constant inflammatory response and that would modify the way solutions behave intravenously, that is how long they remain inside. Having said this, we wish to describe the way colloid solutions behave in this group of patients by taking serial blood samples in 12 obese patients after a colloid infusion, to calculate plasma dilution curves based on hemoglobin dilution and therefore infer the time it remains intravascularly. All this in the hope this information will help, in the near future, to establish a more objective way to use these solutions and avoid possible complications due to over-administration.
Study Type
INTERVENTIONAL
Allocation
NA
Masking
NONE
Enrollment
12
National Institute of Medical Sciences, Salvador Zubiran
Mexico City, Mexico City, Mexico
RECRUITINGdescription of colloid volume kinetics in obese patients after the infusion of Tetrastarch (130/0.4)
different kinetic parameters will be used to asses the behavior of the colloid solution
Time frame: 90 minutes after beginning of the infusion
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