Guided Bone Regeneration Using Synthetic Membrane

Inclusion Criteria: * Subject must have voluntarily signed the informed consent form before any study related action * Age: 18 to 65 with missing teeth, seeking for implant therapy. * Men/Women * In good systemic health * Present with no contra indication against oral surgical interventions * Single/ multiple tooth gap - have at least one missing tooth in the mandible or maxilla, requiring one or more dental implants. * The tooth at the implant site(s) must have been extracted or lost at least 6 weeks before the date of implantation. * Bone defect(s) must be present with a lateral dimension greater than or equal to 5 mm or less. * Full mouth plaque score (FMPI) lower or equal than 25% * Patients must be committed to the study Exclusion Criteria: * Medical conditions requiring prolonged use of steroids * Use of Bisphosphonate intravenously * Current pregnancy or breastfeeding women * Alcoholism or chronically drug abuse * Immunocompromised patients * Uncontrolled Diabetes * Conditions or circumstances, in the opinion of the investigator, which would prevent completion of study participation or interfere with analysis of study results, such as history of non-compliance, or unreliability. * Untreated inflammation * Mucosal diseases or oral lesions * History of local irradiation therapy * Persistent intraoral infection * Patients with bad oral hygiene or unmotivated for normal home care.