Genetic polymorphism affects plasma concentration of antiretroviral therapy in HIV patients. The investigators investigate the prevalence of genetic polymorphism affecting efavirenz metabolism and the corresponding pharmacokinetics of different genotypes.
Eligible patients are invited to donate blood samples for pharmacokinetic study and genotype analysis
Study Type
OBSERVATIONAL
Enrollment
100
The Chinese University of Hong Kong
Hong Kong, Hong Kong, China
pharmacokinetics
This includes plasma concentration of drugs in relation to time, in different genotypes
Time frame: 24 hour
genotypes frequency
Time frame: 1 year
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