Neurally adjusted ventilatory assist (NAVA) is a new mode of mechanical ventilation that delivers ventilatory assist in proportion to neural effort. It was a controlled randomized single-center prospective study in order to explore the efficacy of this new mode of mechanical ventilation after corrective open-heart surgery for congenital heart disease.
1. To evaluate the effect of the patient-ventilator interaction in children underwent open-heart surgery when ventilated with NAVA, compared with conventional mechanical ventilation. 2. To verify the benefits of NAVA in improving the gas exchange and hemodynamics after biventricle repair for CHD.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
72
patients ventilated with the mode of neurally adjusted ventilatory assist after corrective open-heart surgery
Patients ventilated with the mode of pressure support ventilation after corrective open-heart surgery
Cardiac intensive care unit, Department of cardiothoracic vascular surgery, Shanghai Children's Medical Center, Medical college of Shanghai Jiaotong University
Shanghai, China
RECRUITINGAsynchrony index and Comfort Scale
Time frame: 2 weeks
Dosage of sedatives
Time frame: 2 weeks
hemodynamics
Time frame: 2 weeks
Duration of mechanical ventilation
Time frame: 2 weeks
Gas exchange
Time frame: 2 weeks
Length of ICU stay
Time frame: 2 weeks
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