Intraoperative and Postoperative Outcomes of Three Ophthalmic Viscosurgical Devices During Phacoemulsification

Iladevi Cataract and IOL Research Center120 enrolled

Overview

Ophthalmic Viscosurgical Devices (OVDs) play a crucial role during phacoemulsification, by providing endothelial protection, maintaining space, as well as facilitating surgical maneuvers, including IOL implantation. Equally important is the ease of use, good visualisation and easy removal of the OVD from the eye. Currently, 3 popularly used OVDs as a single injection sufficing for surgery are: Healon 5, DiscoVisc, and Celoftal (2% hydroxypropylmethylcellulose). Whereas, there are studies showing efficacy of each of these in clinical scenarios, there is no randomized trial comparing intraoperative performance and postoperative outcomes. The aim of this study was to compare intraoperative performance and postoperative outcomes following microcoaxial phacoemulsification when using one of the three OVDs

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

120

Conditions

Intraoperative Performance and Postoperative Outcomes Following Cataract Surgery

Interventions

Eligibility

Sex: ALLMin age: 45 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age related, uncomplicated senile cataracts Exclusion Criteria: * presence of glaucoma, * shallow anterior chamber (ACD \< 2.1mm), * pupillary dilatation \< 6mm, * extremely dense cataracts, * posterior polar cataract, * subluxated cataract, * white mature cataract, * diabetic retinopathy, * high myopia (defined as AL \> 25mm), * uveitis, or * previous ocular trauma/surgery.

Outcomes

Primary Outcomes

Corneal clarity on postoperative day 1

Time frame: postoperative day 1

Secondary Outcomes

Central corneal thickness on postoperative day 1 and week 1

Time frame: day 1 and week 1